Tuesday, 7 February 2017

Why Do We Feel Hot And Cold As Pain

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On the face of things, a hot waffle iron wouldn't seem to have all that much in common with a block of ice. But the two objects share the same capacity to inflict pain. Extreme heat and extreme cold are both able to deliver a nasty blow to human skin, and it turns out that the brain monitors these thermal extremes in similar ways.

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Sunburn sensitizes our heat-detecting channel, lowering the threshold at which we feel pain. The best understood of them is called TRPV1, and it responds to extreme heat. ... Together these three proteins – TRPV1, TRPM8, and TRPA1 – enable the skin to detect a range of temperatures and the body to respond accordingly.

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