Nobody knows precisely why it works, but doctors have known for decades that the healing process for open wounds can be greatly speeded up by applying negative pressure - that is, suction - under a bandage sealed tightly over the affected area. The speculation is that it helps by drawing bacteria and fluid away from the wound, keeping it cleaner.
For patients, there is a benefit even beyond the speedier healing. Traditional dressings need to be removed and replaced - sometimes painfully - up to three times a day, but with the negative pressure system dressings can be left in place for a few days.
(via Boing Boing)
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